Commit c2099a77 authored by Andreas Tille's avatar Andreas Tille
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New upstream version 4.9i+dfsg

parent 4a2cb6d7
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@@ -8,6 +8,41 @@ discussion site
https://groups.google.com/forum/#!forum/pamlsoftware.


Version 4.9i, March 2019

(*) mcmctree: I have added an option (duplication = 1) for dating a
tree with both speciations and gene duplications, so that some nodes
on the tree share divergence times.  Nodes sharing ages are identified
using labels in the tree file: #1, #2, ....  I have yet to update the
document about specification of the model.

(*) mcmctree: The TipDate option was written for one locus or
partition and never worked for more than two loci/partitions.  I have
edited the code so that it works for multiple partitions, some of
which may be molecular and the others morphological.

(*) codeml: The option estFreq = 0 when codonFreq = 6 (FMutSel0) and 7
(FMutSel) is not working in versions 4.9g and 4.9h.  This is fixed
now.  This option uses the observed codon or amino acid frequencies
for the mutation-selection models of codon usage.  Instead the program
estimates the frequencies using maximum likeihood, which is what the
option estFreq = 1 does.  Look at the README file in the
examples/mtCDNAape/ folder.

(*) codeml clade model D: The bounds for the w (dN/dS) ratios in the
first site classes are set tp (0.0001, 0.5) for w0 and (0.5, 1.5) for
w1, in versions 4.9b,c,d,e,f,g, since I added the BEB calculation for
clade model D in 4.9b.  The motivation for the bounds is that site
class 0 represents strong purifying selection with a small w0, while
site class 1 should include sites under weak purifying selection with
a larger w1.  However the bounds are arbitrary.  In some datasets, the
MLEs are found to be at the bounds, making the interpretation awkward.
I have changed the bounds to the following: 
w0b[]={0.0001, 1.0}, w1b[]={0.01, 1.5}.
This means that the user should swap the estimates of w0 and w2 if w0 > w1.



Version 4.9h, March 2018

(*) mcmctree: gamma-Dirichlet versus conditional i.i.d. priors for

doc/pamlHistory.txt~

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((((human, (chimpanzee, bonobo)) '>.06<.08', gorilla),
(orangutan, sumatran)) '>.12<.16', gibbon);

((((human, (chimpanzee, bonobo)) '>.06<.08', gorilla), (orangutan, sumatran)) '>.12<.16', gibbon);

//end of file


((((human, (chimpanzee, bonobo)) 'B(.06, .08)', gorilla),
(orangutan, sumatran)) 'B(.12, .16)', gibbon);
((((human, (chimpanzee, bonobo)) '>.06<.08', gorilla), (orangutan, sumatran)) '>.12<.16', gibbon);

((((human, (chimpanzee, bonobo)) 'B(.06, .08)', gorilla), (orangutan, sumatran)) 'B(.12, .16)', gibbon);
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    fix_kappa = 0   * 0: estimate kappa; 1: fix kappa at value below
        kappa = 2   * initial or fixed kappas
 
    fix_alpha = 0   * 0: estimate alpha; 1: fix alpha at value below
    fix_alpha = 1   * 0: estimate alpha; 1: fix alpha at value below
        alpha = 0.25   * initial or fixed alpha, 0:infinity (constant rate)
        ncatG = 5   * # of categories in the dG, AdG, or nparK models of rates
      fix_rho = 1   * 0: estimate rho; 1: fix rho at value below
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