diff --git a/debian/changelog b/debian/changelog
index eebb43b09d50dd06bf331074cca50281964ca662..0e2b5edaeb9a7f9c9e4b65a0e193b64ac4883380 100644
--- a/debian/changelog
+++ b/debian/changelog
@@ -6,6 +6,9 @@ libapache2-mod-python (3.5.0+git20211031.e6458ec-1) UNRELEASED; urgency=medium
* Drop patches, superseded upstream: 04_html-escape.patch,
05_fix_spelling.patch, 07_fix-compilation-with-python-3.7.patch,
09_create-DESTDIR-BINDIR-if-needed.patch.
+ * Patches to add Python 3.10 support: (Closes: #1009243)
+ - 11_py310_py_ssize_t_clean.patch
+ - 12_py310_collections_import.patch
-- Stefano Rivera <stefanor@debian.org> Sun, 17 Apr 2022 19:12:13 -0400
diff --git a/debian/patches/11_py310_py_ssize_t_clean.patch b/debian/patches/11_py310_py_ssize_t_clean.patch
new file mode 100644
index 0000000000000000000000000000000000000000..1eb3b260ef4a2ef49cfd88e6b0cbc4d39a373657
--- /dev/null
+++ b/debian/patches/11_py310_py_ssize_t_clean.patch
@@ -0,0 +1,80 @@
+From: Andreas Hasenack <andreas.hasenack@ubuntu.com>
+Date: Sun, 17 Apr 2022 19:30:27 -0400
+Subject: Make mod-python PY_SSIZE_T_CLEAN
+
+Required for Python 3.10 support.
+
+Bug-Debian: https://bugs.debian.org/1009243
+Bug-Ubuntu: https://bugs.launchpad.net/ubuntu/+source/libapache2-mod-python/+bug/1960088
+Forwarded: https://github.com/grisha/mod_python/pull/114
+---
+ src/connobject.c | 2 +-
+ src/filterobject.c | 2 +-
+ src/include/mod_python.h | 1 +
+ src/include/mod_python.h.in | 1 +
+ src/requestobject.c | 2 +-
+ 5 files changed, 5 insertions(+), 3 deletions(-)
+
+diff --git a/src/connobject.c b/src/connobject.c
+index 6f029a4..82cf195 100644
+--- a/src/connobject.c
++++ b/src/connobject.c
+@@ -232,7 +232,7 @@ static PyObject * conn_readline(connobject *self, PyObject *args)
+ static PyObject * conn_write(connobject *self, PyObject *args)
+ {
+ char *buff;
+- int len;
++ Py_ssize_t len;
+ apr_bucket_brigade *bb;
+ apr_bucket *b;
+ PyObject *s;
+diff --git a/src/filterobject.c b/src/filterobject.c
+index 966d2f8..712dbb4 100644
+--- a/src/filterobject.c
++++ b/src/filterobject.c
+@@ -315,7 +315,7 @@ static PyObject *filter_write(filterobject *self, PyObject *args)
+ {
+
+ char *buff;
+- int len;
++ Py_ssize_t len;
+ apr_bucket *b;
+ PyObject *s;
+ conn_rec *c = self->request_obj->request_rec->connection;
+diff --git a/src/include/mod_python.h b/src/include/mod_python.h
+index 68a77d4..69f0214 100644
+--- a/src/include/mod_python.h
++++ b/src/include/mod_python.h
+@@ -43,6 +43,7 @@
+ */
+
+ /* Python headers */
++#define PY_SSIZE_T_CLEAN
+ #include "Python.h"
+ #include "structmember.h"
+
+diff --git a/src/include/mod_python.h.in b/src/include/mod_python.h.in
+index 7d536c5..8d97c47 100644
+--- a/src/include/mod_python.h.in
++++ b/src/include/mod_python.h.in
+@@ -43,6 +43,7 @@
+ */
+
+ /* Python headers */
++#define PY_SSIZE_T_CLEAN
+ #include "Python.h"
+ #include "structmember.h"
+
+diff --git a/src/requestobject.c b/src/requestobject.c
+index 65d42ac..38b7165 100644
+--- a/src/requestobject.c
++++ b/src/requestobject.c
+@@ -1576,7 +1576,7 @@ static PyObject * req_update_mtime(requestobject *self, PyObject *args)
+
+ static PyObject * req_write(requestobject *self, PyObject *args)
+ {
+- int len;
++ Py_ssize_t len;
+ int rc;
+ char *buff;
+ int flush=1;
diff --git a/debian/patches/12_py310_collections_import.patch b/debian/patches/12_py310_collections_import.patch
new file mode 100644
index 0000000000000000000000000000000000000000..42026e8b215c9338fbb85cdbfa1c98343f3ec1c7
--- /dev/null
+++ b/debian/patches/12_py310_collections_import.patch
@@ -0,0 +1,46 @@
+From: Andreas Hasenack <andreas.hasenack@ubuntu.com>
+Date: Sun, 17 Apr 2022 19:31:55 -0400
+Subject: Python 3.10 support: import Callable from collections.abc
+
+Bug-Debian: https://bugs.debian.org/1009243
+Bug-Ubuntu: https://bugs.launchpad.net/ubuntu/+source/libapache2-mod-python/+bug/1960088
+Forwarded: https://github.com/grisha/mod_python/pull/114
+---
+ lib/python/mod_python/publisher.py | 4 ++--
+ lib/python/mod_python/util.py | 4 ++--
+ 2 files changed, 4 insertions(+), 4 deletions(-)
+
+diff --git a/lib/python/mod_python/publisher.py b/lib/python/mod_python/publisher.py
+index 75d103f..5882e77 100644
+--- a/lib/python/mod_python/publisher.py
++++ b/lib/python/mod_python/publisher.py
+@@ -51,8 +51,8 @@ def _callable(obj):
+ if PY2:
+ return callable(obj)
+ else:
+- return (isinstance(obj, collections.Callable) or
+- (hasattr(obj, "__call__") and isinstance(obj.__call__, collections.Callable)))
++ return (isinstance(obj, collections.abc.Callable) or
++ (hasattr(obj, "__call__") and isinstance(obj.__call__, collections.abc.Callable)))
+
+ ####################### The published page cache ##############################
+
+diff --git a/lib/python/mod_python/util.py b/lib/python/mod_python/util.py
+index 67d6b3f..30601a5 100644
+--- a/lib/python/mod_python/util.py
++++ b/lib/python/mod_python/util.py
+@@ -368,12 +368,12 @@ class FieldStorage:
+ filename = None
+ if b"filename" in disp_options:
+ filename = disp_options[b"filename"]
+- if file_callback and isinstance(file_callback, collections.Callable):
++ if file_callback and isinstance(file_callback, collections.abc.Callable):
+ file = file_callback(filename)
+ else:
+ file = tempfile.TemporaryFile("w+b")
+ else:
+- if field_callback and isinstance(field_callback, collections.Callable):
++ if field_callback and isinstance(field_callback, collections.abc.Callable):
+ file = field_callback()
+ else:
+ file = BytesIO()
diff --git a/debian/patches/series b/debian/patches/series
index f4d09b9e91c091bb79a9016295a28a0bfe376759..719bc7c1eca964ca8f3794aaa150ba41d17f5335 100644
--- a/debian/patches/series
+++ b/debian/patches/series
@@ -2,3 +2,5 @@
02_makefile.patch
03_ignore-git-version.patch
10_make-package-reproducible.patch
+11_py310_py_ssize_t_clean.patch
+12_py310_collections_import.patch